EFFECTS OF UREAPLASMA UREALYTICUM ON FAS LIGAND EXPRESSION IN RAT SERTOLI CELL
EFFECTS OF UREAPLASMA UREALYTICUM ON FAS LIGAND EXPRESSION IN RAT SERTOLI CELL
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摘要:
To investigate the effect of ureaplasma urealyticum (UU) on the expression of Fas ligand (FasL) on rat Sertoli cell Materials & Method Isolated rat Sertoli cells were infected by living UU, UU super- natants, inactivated UU, then Fluorescence Activated Cell Sorter and observed fluores- cence microscopy were used to assay for the FasL expression on the surface of Sertoli cells. Results UU infection could increase the expression of FasL in Sertoli cell. Conclusion The functional expression of FasL is related to the immune privilege and can give the immune regulation on the testis.