杜仲和西伯利亚人参的化学成分及药理作用

• 作者: DEYAMA Takeshi NAKAZAWA Yoshihisa NISHIBE Sansei
• 来源期刊: 中国药理学报（英文版）
• 学科: 医学
• 关键词: 药用植物 中国传统医学 木脂素类 葡糖苷类 松烯类 应激 抗高血压药 消化性溃疡 疲劳
• 年，卷（期）: 2001,（12）
• 所属期刊栏目: Review
• 页码范围: 1057-1070
• 页数: 14页
• 分类号: R28
• 语种: 英文

摘要

The bark and leaves of Eucommia ulmoides Oiiv ( Eucommiaceae ) and "Siberian ginseng" ( Ezoukogi in Japanese) prepared from the root bark or stem bark of Eleutherococcus senticosus Maxim ( Acanthopanax senticosta Harms) have been used as tonic and anti-stress drug. The extracts of Eucommia showed anti-hypertensive, anti-complementary, anti-oxidative, and antigastric ulcer effects, and promoting collagen synthesis, accelating granuloma formation, and other pharmacological effects. The Siberian ginseng exhibited anti-fatigue,anti-stress, immuno-enhancing effect, CNS activity, and anti-depressive effect. By now, 40, 28, and 10 compounds have been isolated from Eucommia ulmoides bark, Eucommia ulmoides leaves, and Siberian ginseng,respectively, and their structures were elucidated. Their pharmacological activities were mainly due to lignans and iridoid glycosides.