Syntheses, Crystal Structures and Cytotoxities of Silver(Ⅰ)Complexes of 2,2'-Bipyridines and 1,10-Phenanthroline

• 来源期刊: 中国化学（英文版）
• 学科: 化学
• 年，卷（期）: 2001,（3）
• 页码范围: 263-267
• 页数: 5页
• 分类号: O6
• 语种: 英文

摘要

The syntheses, characterizations and in vitro cytotoxities of seven soluble silver(Ⅰ) compounds (1-7) with 2,2'-bipyridine (bpy), 5,5'-dimeth yl-2,2'-bipyridine (dmbpy) and 1,10-phenanthroline (phen) are described. Two of the complexes, [Ag(dmbpy)(NO3)] (1) and [Ag(dmbpy)]ClO4(2),have been structurally established by single-crystal X-ray diffraction, which reveals the silver(1) atom in compound 1 is in a y-shape coordination geometry with two N atoms (av.Ag－N = 227.8 pm) from a chelate dmbpy ligand and an O atom (Ag-O=221.8(4) pn) from a monodentate nitrate.The Ag(Ⅰ) atom in compound 2 is three-coordinated by three N atoms, two of which are from a chelate dmbpy, and one from an acetonitrile ligand. The seven compounds showed strong cytotoxities in vitro to both normal and carcinoma