THE STRUCTURE OF PHYSALIN T FROM PHYSALIS ALKEKENGI VAR.FRANCHETI

• 来源期刊: 亚洲天然物产研究（英文版）
• 学科: 生物学
• 关键词: Physalin 16,24-cyclo-13,14-secosteroid Physalis alkekengi var. francheti
• 年，卷（期）: 2001,（3）
• 页码范围: 199-205
• 页数: 7页
• 分类号: Q94
• 语种: 英文

摘要

A new steroidal constituent named physalin T (3) was isolated from the aqueous extract of Physalis alkekengi var. francheti. Based on 1H and 13C NMR spectral studies the structure was assigned as 2,3-dihydrophysalin D, i.e., 5α,6β-dihydroxy-2,3,5,6-tetrahydrophysalin B, which is the first example of a natural physalin possessing a saturated ring A moiety. The structure was confirmed by the chemical transformation from the known physalin D (2) to physalin T.