HEPATITIS G VIRAL RNA CO-INFECTION IN PLASMA AND PERIPHERAL BLOOD MONONUCLEAR CELLS IN PATIENTS WITH HEPATITIS C

• 来源期刊: 同济医科大学学报(外文版)
• 学科: 医学
• 关键词: 国外医学 新型肝炎病毒 流行病学 传染病学 研究概况 科学出版社 分子克隆
• 年，卷（期）: 2001,（3）
• 页码范围: 238-239
• 页数: 2页
• 分类号: R373
• 语种: 中文

摘要

The incidence of the co-infection of hepatitis G virus (HGV) and hepatitis C virus (HCV) and its clinical implication was investigated and the difference in the positive rate of HGV RNA and HCV RNA between plasma and peripheral blood mononuclear cells (PBMCs) observed. By using reverse transcriptase polymerase chain reaction (RT-PCR) assay, HCV-RNA and HGV-RNA in plasma and PBMCs of 72 patients with hepatitis C was detected. It was showed that HGV RNA was positive in plasma of 11 patients, in PBMCs of 15 patients, and simultaneously in both of plasma and PBMCs of 10 patients with the co-infection rate being 22.2 %. Nine patients were both HGV RNA and HCV RNA positive in plasma, 11 patients were both HGV RNA and HCV RNA positive in PBMC, and 6 patients were both HGV RNA and HCV RNA positive in both plasma and PBMC with the positive rate being 12.4 %,15.3 % and 8.3 % respectively. The positive rate of both HGV RNA and HCV RNA in PBMCs was higher than in plasma. It was concluded that the HGV co-infection rate in the patients with hepatitis C was 22.2 %. Simultaneous examination of plasma and PBMC can improve clinically detectable rate.