Synthesis of Novel Chiral Biphenylamine Ligand 6,6′- Dimethoxy-2,2′- diaminobiphenyl

• 来源期刊: 中国化学（英文版）
• 学科: 化学
• 年，卷（期）: 2001,（8）
• 所属期刊栏目: Articles
• 页码范围: 794-799
• 页数: 6页
• 分类号: O6
• 语种: 英文

摘要

A new chiral ligand 6,6′-dimethoxy-2,2′-diaminobiphenyl was successfully prepared from 3-nitrophenol via iodination, Ulmann coupling, and reduction. The resolving reagent (2R,3R)- or (2S,3S)-2,3-di(phenylaminocarbonyl)tartaric acid was prepared from commercially available tartaric acid in large scale and was used to resolve the racemic 6,6′- dimethoxy-2,2′-diaminobiphenyl. The chiral 6,6′- dimethoxy-2,2′-diaminobiphenyl obtained was proved to be enantiomerically pure.