紫外分光光度法测定羟氨苄青霉素咀嚼片的尿药浓度及生物利用度的研究

• 作者: 李忠忠 赵春洁
• 来源期刊: 中华现代临床医药杂志
• 学科: 医学
• 关键词: UV Amoxicillin Bioavailability
• 年，卷（期）: 2002,（7）
• 所属期刊栏目: 药物与临床应用
• 页码范围: 42-43
• 页数: 2页
• 分类号: R9
• 语种: 中文

摘要

Objective To establish an UV method for the determination of amoxicillin chewing tablets in urine andbioavailability. Methods Determination of amoxicillin chewing tablets in urine and bioavailability by UV at 325nm. ResultsA good linear relationship was obtained for 6 ～ 60μgml - 1, r = 0.9992. Intra - day and inter - day RSD were small 2.01% and2.94%.The recovery was 99.10+ 1.25%(n = 6).Conclusion A simle, highly sensitive and selective method for thcdetermination of amoxicillin chewing tablets in urine was established, which could be used for its pharmacokinetic andbioavailability studies.

作者信息

序号	姓名	单位	发文数	被引次数	H指数	G指数
1	李忠忠		8	18	3.0	4.0
2	赵春洁		1	0	0.0	0.0