Reiter′s syndrome is a secondary disease of urethrainfection. It consists of urethritis, nonsuppurativearthritis, conjunctivitis and cutaneous mucosa lesions.Young males are more likely to get Reiter′s syndromethan females. Thus far, there are no reports of womenin China with Reiter's Syndrome.1-4 This reportdocuments two females with Reiter's Syndrome.