Objective To study the treatment for severe acute ascites pancreatitis by celiocentesis drainage. Methods To sum up 20cases of severe acute ascites pancreatitis diagnosed by Ultrasamd B from 1999 ~ 2000 and the effect of celiocentesis combined withmedicines.Results The effective rate is 85% (17 cases). The ineffective rate is 15% (3 cases inclucling 2 cases of peripancreaticabscess and 1 cases of MOF). Conclusion The therapy is effective.