New Chiral Substituted 8-Quinolinyl-oxazolines as Ligands for Copper (I) -catalyzed Asymmetric Cyclopropanation

• 来源期刊: 中国化学(英文版)
• 年，卷（期）: 2002,（11）
• 页码范围: 1445-1449
• 页数: 5页
• 语种: 英文

摘要

New chiral substituted 8-quinolinyl-oxazoline ligands have been syntesized and applied in the copper(I)-catalyzed asymmetric cyclopropanation of styrene with alkyl diazoacetates. The steric effect in the ligands plays a significant role in the enantiocontrol in asymmetric cyclopropanation, while the electronic effect is less important.