乳腺癌患者血清CA15～<em>3</em>和TPS表达水平及其临床价值

• 作者: 候蓉 原荣 张俊 李军 王玉珍 苗爱莲 魏曙亚
• 来源期刊: 美国中华健康卫生杂志
• 学科: 医学
• 关键词: Breast cancer Tumor marker CA15-3TPS
• 年，卷（期）: 2002,（6）
• 所属期刊栏目: 辅助检查
• 页码范围: 61-63
• 页数: 3页
• 分类号: R73
• 语种: 中文

摘要

Objective To study the clinical value for breast cancer by combining testing the serumexpression levels of CA15-3and Tissue polypeptide specific antigen(TPS).Methods CA15-3 and TPS inserum sample of 92 cases of patients with breast cancer were analysed by using ELISA in two weeks beforeand after treatment of operation and drugs. Results The values of CA15 ～ 3 and TPS in serum were highersignificanec in patients with breast cancer than those in the control group of healthy subjects and breastbenign diseases goup(P ＜ 0.01). Expression levels of CA15～3 in serum were significance increased with TNM staging and TPS with clinical one to two stage. The serum levels of CA15- 3 and TPS in the breastcancer patients with treatment of surgery were markly decreased in two weeks after operation(P ＜ 0.01 )and no changed in the patients without operation whose condition was stable and it was significantly in-creased the patients with progressive and relapse especially TPS. Conelusion CA15 ～ 3 and TPS can beused as useful tumor markers of breast cancer in diagnosis of early stage, evaluating of therapeutic effect,assessing the prognosis of the disease, and it is highly usefulin monitoring recurrences of breast cancer, es-pecially dynamic detection.

作者信息

序号	姓名	单位	发文数	被引次数	H指数	G指数
1	李军		38	210	9.0	12.0
2	魏曙亚		13	54	4.0	6.0
3	候蓉		5	20	2.0	4.0
4	王玉珍		19	38	4.0	5.0
5	原荣		26	95	6.0	8.0
6	苗爱莲		1	0	0.0	0.0
7	张俊		1	0	0.0	0.0