Objective To observe the characteristic of nursing patients with nasopharyngeal carcinoma who receivechemotherapy in outpatient. Method Collecting datum of 89 cases who received DDP + 5 - FU chemotheropy from January1998 to September, 1998 collecting the various reaction, and stressing nursing and prevention. Result The patients sufferedfrom such reactions as gastro - intestinal reaction, arrest of bone barrow. Stomatitis, diarrhea, constipation, shiver fever andphlebitis. Conclusion The reactions should be treated in time.