Reaction microscope is a powerful tool for studying ion-atom/molecule dynamics, it can also be employed to investigate electron impact ionization processes. Traditionally these processes are studied by using the (e, 2e) or (e, 3e) techniques, most data are collected for single ionization and for very small scattering angles, i.e. (e, 2e), experimental data of double ionization (e, 3e)[1] and multiple ionization are scarce, because in most cases the efficiencies (mainly determined by solid angles) are extremely small for (e, 3e) processes, about 10^-7~10^-9. On the other hand, the new technique-reaction microscope can detect mutli-fragments in one collision with very