以脉波分析法评价中草药方

• 作者: 徐则林 王唯工 王林玉英 鲍建国
• 来源期刊: 中国药理学报（英文版）
• 学科: 医学
• 关键词: 脉波分析 中国传统医学 六味地黄 八味地黄
• 年，卷（期）: 2003,（2）
• 所属期刊栏目: 研究原著
• 页码范围: 145-151
• 页数: 7页
• 分类号: R28
• 语种: 英文

摘要

AIM: To distinguish the component difference between two similar herbal formulas by pulse analysis method.Many Chinese herbs were found to have specific effects on the Fourier components of the blood pressure pulse; itmight infer a specific blood redistribution process on the body and reflect the health conditions of specific organsor tissues. The pulse effect of an herbal formula was similar to the linear combination of all its herbal compositions.METHODS: Two different versions of the herbal formula Liu-Wei-Dihuang were fed to the Wistar rats as a singleblind test. The blood pressure pulses on the rat tail artery were recorded and then transformed to the frequencydomain by Fourier analyzer. RESULTS: Formula A, Bai-Wei-Dihuang, with two more herbs Cortex Cinnamomiand Radix Aconiti added to Liu-Wei-Dihuang, increased the harmonic proportion of the 1st harmonic (C1) butdecreased C4, C5. Formula B is composed in the same way but without Rhizoma Batatatis and Poria cocos; itincreased the DC of the pulse spectrum (CO), but decreased C2, C3, C4, C5, C6. CONCLUSION: The componentadjustment of an herbal formula could be distinctly and quantitatively detected by pulse analysis method.