EXPRESSION CHANGES IN TAU AND MICROTUBULE-ASSOCIATED PROTEINS IN RAT TESTICULAR INTERSTITIUM

• 来源期刊: 亚洲男性学杂志(英文版)
• 学科: 生物学
• 年，卷（期）: 2004,（1）
• 页码范围: 52
• 页数: 1页
• 分类号: Q819
• 语种: 中文

摘要

Objective: To examine the expression of the tau protein and mi-crotubule-associated proteins (MAP) in the testicular interstitium of aged and young rats. Methods: Sprague-Dawley male rats were divided into a young group (6 months) and an aged group (28 months) of 10 animals each. The two-step immunohistochemistry method with the antibody against tau protein and MAPa was performed with the testis tissues. Results: The immunoreactive cells of the testicular interstilial tau protein were significantly increased (P<0.01) and those of the MAP significantly decreased (P<0.01) in the aged than in the young rats. Conclusion: The changes in the expression of the tau protein and MAP may be related to the aging process of the testis.