Unraveling Mystery of Enhanced Cell-killing Effect around Bragg Peak Region of a Double Radiation Source 9C-ion Beam

• 作者: Li Qiang Y. Furusawai M. Kanazawai T. Kanai A. Kitagawa
• 来源期刊: 近代物理研究所和兰州重离子加速器实验室年报：英文版
• 学科: 物理学
• 关键词: Bragg峰 离子束 杀伤 细胞 影响区 辐射源 生物学实验 生物物理机制
• 年，卷（期）: 2004,（1）
• 页码范围: 88
• 页数: 1页
• 分类号: O571.426

摘要

<正>An enhanced cell-killing effect at the penetration depths around the Bragg peak of a β-delayed particle decay 9C -ion beam has been observed in our preceding radiobiological experiments in comparison with a therapeutic 12C beam under the same conditions, and RBE values of the 9C beam were revealed to be higher than those of the comparative 12C beam by a factor of up to 2. This study was aimed at investigating the biophysical mechanisms underlying the important experimental phenomenon.