Synthesis, Structure and Biological Activity of Zn(II) Complex with Tris(benzimidazol-2-yl-methyl)amine Ligand

• 来源期刊: 中国化学（英文版）
• 学科: 化学
• 年，卷（期）: 2004,（1）
• 页码范围: 75-79
• 页数: 5页
• 分类号: O6
• 语种: 英文

摘要

A new Zn(II) mononuclear complex with tris(benzimidazol-2-yl-methyl)amine (NTB) was synthesized with stoichiometry of [Zn(NTB)NO3]NO3·DIPY·DMF (DIPY∶4,4'-dipyridyl). The complex was characterized by elemental analysis, UV and IR spectra. The crystal structure was determined by using X-ray diffraction analysis. The crystal structure indicates that four N atoms and one O atom coordinate to zinc ion to construct a distorted trigonal-dipyramid configuration. Three nonprotonated N atoms from imidazole groups are in the equatorial plane, one alkylamino N atom and one O atom from in the axial directions. The biological activity assay shows that this complex presents certain biological activity by means of pyrogallol autoxidation and it can be called a model compound of superoxide dismutase (SOD).