Synthesis of an Analogue of Squalamine: 6β-Hydroxyl-3-aminosterol

• 来源期刊: 中国化学（英文版）
• 年，卷（期）: 2004,（9）
• 页码范围: 1019-1021
• 页数: 3页
• 语种: 英文

摘要

6β-Hydroxylsqualamine was synthesized stereoselectively in 13 steps and 19% overall yield from methyl hyodeoxycholanate by using stereospecific epoxidation and asymmetric isopropylation as key steps.