Synthesis, Characterization and Electrochemical Behavior of Hepta- O-acetyl-β-lactosyl Isothiocyanate

• 来源期刊: 中国化学(英文版)
• 年，卷（期）: 2005,（5）
• 页码范围: 543-547
• 页数: 5页
• 语种: 英文

摘要

A new compound of hepta-O-acetyl-β-lactosyl isothiocyanate has been synthesized and its structure was deter mined by X-ray crystallography. The compound crystallizes in the orthorhombic system, with space group P212121 and cell dimensions of a=1.23282(7) nm, b=1.80012(10) nm, c= 1.85230(10) nm, α=β=γ=90°, V=4.1107(4)nm3, and Z=4. The electrochemical experimental results indicate that both dsDNA and ssDNA had obvious reduction effect on the peak current of the title compound, which was bound to DNA mainly through electrostatic binding.