TARGETING GENE-VIROTHERAPY OF CANCER AND ITS PROSPERITY

• 来源期刊: 细胞研究(英文版)
• 学科: 生物学
• 关键词: 山田 幽州
• 年，卷（期）: 2006,（11）
• 页码范围: 879-886
• 页数: 8页
• 分类号: Q2
• 语种: 英文
• DOI: 10.1038/SJ.CR.7310108

摘要

Gene and viral therapies for cancer have shown some therapeutic effects,but there has been a lack of real break-through.To achieve the goal of complete elimination of tumor xenograft in animal models,we have developed a newstrategy called Targeting Gene-Virotherapy of Cancer,which aims to combine the advantages of both gene therapy andvirotherapy.This new strategy has produced stronger anti-tumor effects than either gene or viral therapy alone.A tumor-specific replicative adenovirus vector,designated as...