One Pot Reduction of Imines Generated in-situ from Aldehydes and Amines by the NaBH4-InCl3 System

• 来源期刊: 中国化学（英文版）
• 年，卷（期）: 2006,（6）
• 页码范围: 807-810
• 页数: 4页
• 语种: 英文

摘要

A combination of sodium borohydride and a catalytic amount of indium(Ⅲ) chloride in acetonitrile reduces imines formed in-situ from aldehydes and amines to the corresponding functionalised secondary and tertiary amines in moderate to good yields. Noteworthy is that highly chemoselective reactions were achieved in the presence of other functional groups such as halogens, carbon-carbon double bonds and hydroxyl groups.