Synthesis of Certain 3-Aminopyrazolo[5,4-b]pyridine and 3,4-Substituted Pyrido[2',3': 3,4]pyrazolo[5,1-c][1,2,4]triazine Derivatives

• 来源期刊: 中国化学（英文版）
• 年，卷（期）: 2007,（12）
• 页码范围: 1887-1891
• 页数: 5页
• 语种: 英文

摘要

2-Thioxo-1,2-dihydropyridine derivatives 2a,2b were reacted with methyl iodide to give 2-methylthiopyridines 3a,3b,which were reacted with hydrazine hydrate to produce 3-aminopyrazolo[5,4-b]pyridines 4a,4b.Compounds 4a,4b were diazotized to afford the corresponding diazonium salts 5a,5b,which were reacted with some active methylene compounds 6a-6h to give the corresponding pyrido[2',3': 3,4]pyrazole[5,1-c] [ 1,2,4]triazines 7-14.