Baylis-Hillman Reactions of Sulfonyl Aldimines or Aryl Aldehydes with 3-Methylpenta-3,4-dien-2-one or 3-Benzylpenta-3,4-dien-2-one

• 来源期刊: 中国化学（英文版）
• 年，卷（期）: 2007,（6）
• 页码范围: 828-835
• 页数: 8页
• 语种: 英文

摘要

The attempted Baylis-Hillman reactions of sulfonyl aldimines or aryl aldehydes with 3-methylpenta-3,4-dien-2-one or 3-benzylpenta-3,4-dien-2-one gave the corresponding Baylis-Hillman adducts in moderate yields in DMSO under the catalysis of DBU or PMe3, respectively. Moderate diastereoselectivities were observed in the reaction of 3-benzylpenta-3,4-dien-2-one with N-arylmethylidene-l-naphthalenesulfonamides catalyzed by chiral catalyst cinchona alkaloid derivative TQO {4-(3-ethyl-4-oxa-l-azatricyclo[4.4.0.03,8]dec-5-yl)quinolin-6-ol}.