A Concise and Convenient Synthesis of Stilbenes via Benzils and Arylmethyldiphenylphosphine Oxides

• 来源期刊: 中国化学（英文版）
• 年，卷（期）: 2007,（12）
• 页码范围: 1866-1870
• 页数: 5页
• 语种: 英文

摘要

A new and convenient synthetic method has been developed for the construction of stilbenes bearing electron-withdrawing group(s) by using benzils and arylmethyldiphenylphosphine oxides via sequences involving Wittig-Horner reaction and a rearrangement in the presence of t-BuOK in toluene under mild conditions.This approach could be readily applied to a facile synthesis of biologically important natural products,resveratrol and its derivatives,such as trimethoxystilbenes 1 (Z) and 2 (E).