BIOLUMINESCENCE TOMOGRAPHY: BIOMEDICAL BACKGROUND, MATHEMATICAL THEORY, AND NUMERICAL APPROXIMATION

• 来源期刊: 计算数学（英文版）
• 关键词: Biomedical imaging Bioluminescence tomography (BLT) Inverse problem,Regularization Numerical approximation Error analysis
• 年，卷（期）: 2008,（3）
• 页码范围: 324-335
• 页数: 12页
• 语种: 英文

摘要

Over the last couple of years molecular imaging has been rapidly developed to study physiological and pathological processes in vivo at the cellular and molecular levels. Among molecular imaging modalities, optical imaging stands out for its unique advantages, especially performance and cost-effectiveness. Bioluminescence tomography (BLT) is an emerging optical imaging mode with promising biomedical advantages. In this survey paper, we explain the biomedical significance of BLT, summarize theoretical results on the analysis and numerical solution of a diffusion based BLT model, and comment on a few extensions for the study of BLT.