Amination Reactions of Aryl Halides with Nitrogen-Containing Reagents Catalyzed by Cul in Ionic Liquid

• 来源期刊: 中国化学（英文版）
• 年，卷（期）: 2008,（1）
• 页码范围: 165-169
• 页数: 5页
• 语种: 英文

摘要

CuI-catalyzed coupling reactions of aryl iodides and electron-deficient aryl bromides with nitrogen-containing reagents, such as imidazole, benzimidazole, aliphatic primary and secondary amines, aniline, primary and secondary amides, in ionic liquid were developed. The reaction conditions involved the use of[Bmim][BF4] as the solvent,potassium phosphate as the base, and CuI as the catalyst. The CuI and[Bmim][BF4] could be recovered and recycled for five consecutive trials without significant loss of their activity.