Iodine Catalyzed One-pot Synthesis of 3,4-Dihydroquinazolin-4-ones from Anthranilic Acids, Ortho Esters and Amines under Solvent-free Conditions

• 来源期刊: 中国化学（英文版）
• 年，卷（期）: 2008,（1）
• 页码范围: 175-178
• 页数: 4页
• 语种: 英文

摘要

A simple and efficient procedure has been developed for the one-pot synthesis of 3,4-dihydroquinazolin-4-ones from anthranilic acids, ortho esters and amines using a catalytic amount of iodine under solvent-free conditions to afford the corresponding products in excellent yields. The direct use of commercially available catalyst, mild and solvent-free reaction conditions, short reaction time, easy workup and excellent yields are the advantages of the present protocol.