Further New Cembrane Diterpenes from the Hainan Soft Coral Sarcophyton latum

• 来源期刊: 中国化学（英文版）
• 年，卷（期）: 2008,（1）
• 页码范围: 150-152
• 页数: 3页
• 语种: 英文

摘要

Two new cembranoid diterpenes, diepoxysarcophytonene (1) and sarconphytonol (2), were isolated from the Hainan soft coral Sarcophyton latum. Their structures including relative stereochemistry were established by 1D and 2D NMR spectroscopic techniques. Compound 1 showed weak inhibitory activity against COX-2 in vitro at the concentration of 10-5 μmol·L-1 with the inhibitory rate of 55%.