The task dependent interaction of the deactivation regions

• 来源期刊: 科学通报（英文版）
• 年，卷（期）: 2008,（10）
• 页码范围: 1527-1532
• 页数: 6页
• 语种: 英文
• DOI: 10.1007/s11434-008-0222-8

摘要

Although deactivation has been found frequently in former functional brain imaging researches, only recently has it become a focus of systematic study because of its not well understood physiological mechanism. However, most of the researches concentrated on the brain areas that would present de-activation, and, to our knowledge, the deactivation connectivity between these brain areas during the cognitive tasks has rarely been reported in literature. In this work, using the functional connectivity method WlCA (within-condition interregional covariance analysis), we analyzed the deactivations in two different cognitive tasks-symbol orientation and number comparison. The results revealed de-activations in the posterior cingulate, precuneus, anterior cingulate and prefrontal cortex in both tasks. However, the interaction between the deactivated regions shows many differences. Our result further indicates that the potential implication of special deactivation connectivity may be related to the dif-ferent task or attention resource. Further research is needed to clarify the exact reason.