Dipeptide Formation from Amino Acid Monomer Induced by keV Ion Irradiation: An Implication for Physicochemical Repair by Radiation Itself

• 来源期刊: 等离子体科学和技术（英文版）
• 年，卷（期）: 2008,（1）
• 页码范围: 126-130
• 页数: 5页
• 语种: 英文

摘要

An identification of Phe dipeptide from L-phenylalanine monomers after keV nitro-gen and argon ion implantation, by using the HPLC (high performance liquid chromatography) and LC-MS(liquid chromatography mass spectrometer) methods is reported. The results showed a similar yield behavior for both ion species, namely: 1) the yield of dipeptides under alkalescent conditions was distinctly higher than that under acidic or neutral conditions; 2) for different ion species, the dose-yield curves tracked a similar trend which was called a counter-saddle curve. The dipeptide formation may implicate a recombination repair mechanism of damaged biomolecules that energetic ions have left in their wake. Accordingly a physicochemical self-repair mechanism by radiation itself for the ion-beam radiobiological effects is proposed.