Catalytic Reaction of Aryldiazoacetates with Indole and Its Derivatives: Profound Effect of N-1 Substitutent on the Reaction Pathways

• 来源期刊: 中国化学（英文版）
• 年，卷（期）: 2008,（4）
• 页码范围: 716-720
• 页数: 5页
• 语种: 英文

摘要

The reaction of indole and its derivatives with aryldiazoacetates has been studied in the presence of copper and The electron-donating group favored the formation of the β-alkylation products, while the electron-withdrawing group favored the formation of the cyclopropane products. A reaction mechanism was proposed based on the experimental data and previous research results. The structure of aryl group in diazo compounds also affected the yield of the β-alkylation products or the cyclopropane products.