2-(1 H-Benzotriazole-1-yl)-1,1,3,3-Tetramethyluronium Tetrafluoro Borate (TBTU) as an Efficient Coupling Reagent for the Esterification of Carboxylic acids with Alcohols and Phenols at Room Temperature

• 来源期刊: 中国化学（英文版）
• 年，卷（期）: 2008,（6）
• 页码范围: 1141-1144
• 页数: 4页
• 语种: 英文

摘要

Esterification of carboxylic acids with alcohols and phenols by using 2-(1H-benzotriazole-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate (TBTU) in the presence of triethylamine as a base proceeded smoothly under mild conditions to afford the corresponding esters in good to high yields in acetonitrile at room temperature.