Mild and Efficient Catalytic Protocol for Tetrahydropyranylation of Alcohols Using Acidic Keggin and Wells-Dawson Structures

• 来源期刊: 中国化学(英文版)
• 年，卷（期）: 2008,（12）
• 页码范围: 2273-2277
• 页数: 5页
• 语种: 英文

摘要

A simple, mild and effective procedure is reported to the generation of 2-tetrahydropyranyl acetals from alco-hols. Keggin and Wells-Dawson heteropolyoxometalates were used as catalysts at ambient temperature in acetone as solvent with good yields and high selectivities in a short reaction time. Different reaction parameters affecting ef-ficiency of the protocol were also studied. The use of these acid catalysts allows replacing the usual soluble inor-ganic acids, contributing to waste reduction.