Synthesis, Fluorescence Properties and Biological Activity of 8-Hydroxyquinoline Conjugate Bonded Aromatic Heterocyclic Derivatives

• 来源期刊: 中国化学（英文版）
• 年，卷（期）: 2008,（7）
• 页码范围: 1299-1304
• 页数: 6页
• 语种: 英文

摘要

Four kinds of 8-hydroxyquinoline conjugate bonded aromatic heterocyclic derivatives were designed and syn-thesized for potential use in the emission and electron conduction layers in organic light emitting devices, and as luminescent probes for metal ions. These novel compounds were characterized by IR, 1H NMR,13C NMR, Mass and UV-visible spectra. The photoluminescent properties of the new compounds including the spectra (shape of bands,λex, λem), quantum yield (pf) and lifetime (t) were investigated. Moreover, density functional theory method was used to study the relationship between the geometric configuration and emission wavelength. MTT assays of cell proliferation of rMSC and DPPH radical-scavenging tests suggested that the new compounds generate a sig-nificant increase of rMSC and demonstrate a good antioxidant activity.