Self-condensation of Terminal Acetylenic Ketones vta Organozinc Species

• 来源期刊: 中国化学(英文版)
• 年，卷（期）: 2008,（9）
• 页码范围: 1689-1692
• 页数: 4页
• 语种: 英文

摘要

A self-condensation reaction of a,β-acetylenic ketones via organozinc species CF3CO2ZnEt to afford the β-branched Morita-Baylfis-Hillman adducts has been developed.This reaction system provides functionalized trisubstituted olefins in good yields.Organozinc species CF3CO2ZnCH2I,an efficient cyclopropanation reagent,can also react with aromatic acetylenic ketones to provide 2,5-dihydrofurans in moderate yields.