The entropy characters of point mutation

• 来源期刊: 科学通报（英文版）
• 年，卷（期）: 2008,（19）
• 页码范围: 3008-3015
• 页数: 8页
• 语种: 英文
• DOI: 10.1007/s11434-008-0393-3

摘要

The biological diversity, which depends on the genetic material DNA, is the foundation for a species to survive and evolve. The entropy is the best measurement of biological diversity. Based on the sin-gle-parameter and the two-parameter models, here we established some differential equations about the point mutation of a DNA sequence with finite length, as well as some functions describing the processes of the variation in quantities of 4 kinds of bases (A, T, G and C) in the DNA sequence. At the molecular level, we discussed the entropy characteristics of point mutation. The results proved that a species maintained its entropy and evolved in the direction of the increasing biological diversity. In order to testify the theoretical results, we did a series of computer simulations of random point muta-tion in Matlab environment. The results were well consistent with the theoretical researches.