Synthesis and Bioactivity of Novel M,N'-Diacylhydrazine Derivatives Containing Furan(Ⅰ)

• 来源期刊: 中国化学（英文版）
• 年，卷（期）: 2008,（5）
• 页码范围: 916-922
• 页数: 7页
• 语种: 英文

摘要

The furan ring system possesses electron-rich properties and exhibits various biological activities,which was introduced into diacylhydrazine to create novel leading compounds that may serve as improved pesticides and pharmaceuticals.A series of novel diacylhydrazine derivatives containing a furan ring were synthesized by the reaction of 5-fluorophenyl-2-furoyl chloride with substituted benzoylhydrazide in anhydrous dichloromethane under reflux.The structures of the resultant compounds were confirmed by IR,1H NMR,MS and elemental analysis.Insecticidal and anti-tumor activities of these new compounds were evaluated.