Detection of microarray protein biomolecules by oblique-incidence reflectivity difference technique without labelling agents

• 来源期刊: 中国物理B(英文版)
• 关键词: detection OI-RD protein microarray
• 年，卷（期）: 2008,（6）
• 页码范围: 2288-2291
• 页数: 4页
• 语种: 英文

摘要

This paper reports that the detection to the protein in microarray format is carried out by oblique-incidence reflectivity difference (OI-RD) analysis without any labelling agents. The OI-RD intensities not only depend on the protein structure, but also vary with the protein concentration. The results indicate that this method should have potential application in detection of biochemical processes. The high throughout and in situ detection can be achieved by this method with further improving of the experimental system.