Contrast-enhanced harmonic ultrasound imaging in ablation therapy for primary hepatocellular carcinoma

• 作者: Masatoshi Kudo Yasunori Minami
• 来源期刊: 世界放射学杂志：英文版（电子版）
• 学科: 医学
• 关键词: CONTRAST-ENHANCED HARMONIC ULTRASOUND HEPATOCELLULAR carcinoma RADIOFREQUENCY ablation Second generation MICROBUBBLES
• 年，卷（期）: 2009,（1）
• 页码范围: 86-91
• 页数: 6页
• 分类号: R

摘要

The success rate of percutaneous radiofrequency(RF)ablation for hepatocellular carcinoma(HCC)depends on correct targeting via an imaging technique.However,RF electrode insertion is not completely accurate for residual HCC nodules because B-mode ultrasound(US),color Doppler,and power Doppler US findings cannot adequately differentiate between treated and viable residual tumor tissue.Electrode insertion is also difficult when we must identify the true HCC nodule among many large regenerated nodules in cirrhotic liver.Two breakthroughs in the field of US technology,harmonic imaging and the development of second-generation contrast agents,have recently been described and have demonstrated the potential to dramatically broaden the scope of US diagnosis of hepatic lesions.Contrast-enhanced harmonic US imaging with an intravenous contrast agent can evaluate small hypervascular HCC even when B-mode US cannot adequately characterize tumor.Therefore,contrast-enhanced harmonic US can facilitate RF ablation electrode placement in hypervascular HCC,which is poorly depicted by B-mode US.The use of contrast-enhanced harmonic US in ablation therapy for liver cancer is an efficient approach.