Insulin resistance: β-arrestin development

• 来源期刊: 细胞研究(英文版)
• 年，卷（期）: 2009,（3）
• 页码范围: 275-276
• 页数: 2页
• 语种: 英文
• DOI: 10.1038/cr.2009.22

摘要

Insulin resistance is simply the in-ability of insulin to elicit a physiologic response. While insulin resistance is most commonly associated with the pathogenesis of metabolic disorders such as type II diabetes and obesity, it is also a predisposing factor to a number of other diseases such as cancer and car-diovascular disease . There are just as many theories as to the cause of insulin resistance as there are insulin signal-ing molecules and it is very unclear as to which are the actual molecular mechanisms of insulin resistance in diseased states.