EFFECT OF SERUM FROM OVERFATIGUE RATS ON JNK/C-JUN/HO-1 PATHWAY IN HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS AND THE INTERVENING EFFECT OF TONGXINLUO(通心络)SUPERFINE POWDER

• 来源期刊: 中国结合医学杂志(英文版)
• 学科: 医学
• 关键词: 通心络
• 年，卷（期）: 2009,（2）
• 页码范围: 121-127
• 页数: 7页
• 分类号: R285.5
• 语种: 中文

摘要

Objective:To cultivate human umbilical vein endothelial cells (HUVECs) in the serum of overfatigue rats with the intervention of Tongxinluo (通心络) superfine powder (TXLSP).By examining the variation of the activity of JNK/c-Jun/HO-1 pathway,the possible mechanisms of vascular endothelial dysfunction under overfatigue conditions and the intervening effect of TXLSP were explored.Methods:The HUVECs were randomly divided into the normal control group,the model group,the SP600125 (a specific antagonist of JNK)...