在有主要胆汁的肝硬化的一个病人的肝的反应淋巴的增生

• 作者: Akira Andoh Fumiyoshi Kojima Hidetoshi Okabe Hiroshi Yamamoto Machiko Hotta Mitsuaki Ishida Tamio Nakahara Tohru Tani Tomoyuki Tsujikawa Yasuharu Saito Yoshihide Fujiyama Yousuke Mochizuki
• 来源期刊: 世界肝病学杂志：英文版（电子版）
• 学科: 医学
• 关键词: REACTIVE LYMPHOID HYPERPLASIA PSEUDOLYMPHOMA Liver Primary BILIARY CIRRHOSIS Gastric cancer
• 年，卷（期）: 2010,（10）
• 页码范围: 387-391
• 页数: 5页
• 分类号: R575.2

摘要

Reactive lymphoid hyperplasia(RLH) of the liver is an extremely rare lesion characterized by the proliferation of non-neoplastic lymphocytes forming follicles.Hepatic RLH is known to be associated with gastrointestinal carc inoma and autoimmune diseases including primary biliary cirrhosis(PBC).We report a case of hepatic RLH in a patient with PBC and gastric cancer.A 68 year old Japanese woman with a 10 year history of liver enzyme abnormality was admitted.Laboratory testing revealed that her anti-mitochondrial antibody was markedly elev ated.Five mo after the diagnosis of PBC,she was foun d to have gastric cancer.Abdominal computed tom og raphy disclosed a liver nodule in S8,suggesting metas tatic gastric carcinoma.Histopathologically,the resected liver lesion comprised of a nodular proliferation of small lym phocytes with lymphoid follicles.This is the first reported case of hepatic RLH in a patient with both PBC and gastric cancer.Pre-operative diagnosis of hepatic RLH by clinical imaging is extremely difficult.Therefore,a need le biopsy could be useful to make a diagnosis of hepat ic RLH,especially to differentiate from metastatic gastroin t estinal carcinoma.