Construction of a gene regulatory network for Arabidopsis based on metabolic pathway data

• 来源期刊: 科学通报(英文版)
• 学科: 生物学
• 关键词: 基因调控网络 代谢途径 基因数据 拟南芥 基础 转录因子 基因启动子 生物学功能
• 年，卷（期）: 2010,（2）
• 所属期刊栏目: ARTICLES
• 页码范围: 158-162
• 页数: 5页
• 分类号: Q253 X172
• 语种: 英文

摘要

Elucidation of gene regulatory networks is the key to understanding the complex interplay of transcription factors (TFs) in the growth and propagation of organisms. In this work, we applied the theory that genes belonging to the same pathway are co-expressed, and therefore a promoter analysis of Arabidopsis genes could predict the transcriptional relationships between metabolic pathway genes. Using this approach, a total of 2268 TF-gene pairs were analyzed, 91 of which were characterized as highly confident...