Fountain of Youth: aged blood-forming stem cells could be rejuvenated by young microenvironment
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摘要:
A recent paper published in Nature by Amy J Wagers' group reports a re-markable function ofosteoblastic niche (defined as microenvironment) [1] in reversing the aged phenotype of he-matopoietic (blood-forming) stem cells, thus opening the possibility for clinical treatment of age-related diseases via modifying the stem cell niche.