From a Global View to Focused Examination:Understanding Cellular Function of Lipid Kinase VPS34-Beclin 1 Complex in Autophagy

• 来源期刊: 分子细胞生物学报（英文版）
• 年，卷（期）: 2010,（6）
• 页码范围: 305-307
• 页数: 3页
• 语种: 中文
• DOI: 10.1093/jmcb/mjq028

摘要

Autophagy is a cell'self-digestion'process via lysosomal degradation.The bestknown type of autophagy is macroauto phagy(hereafter referred to as auto phagy).Which involves the formation,delivery and degradation of autophago somes.The physiological function of autophagy is the controI of cellular nutrient and organelle homeostasis and can be regulated by various extracellular and intracellular cues(Klionsky and Emr,2000;Levine and Klionsky.2004).