Detection system for singlet oxygen luminescence in photodynamic therapy

• 来源期刊: 中国光学快报(英文版)
• 学科: 化学
• 关键词: 近红外发光 光动力疗法 检测系统 单线态氧 发光光谱 直接检测 直接测量 注意力
• 年，卷（期）: 2010,（1）
• 所属期刊栏目: Medical Optics and Biotechnology
• 页码范围: 86-88
• 页数: 3页
• 分类号: O614.346 TQ463
• 语种: 英文

摘要

Singlet oxygen(~1O_2) is widely considered to play a major role in photodynamic therapy(PDT),and thus an increasing attention has been focused on the direct detection of ~1O_2 near-infrared luminescence around 1270 nm for PDT dosimetry.A new sensitive detection system is developed to directly measure the temporal and spectral resolved ~1O_2 luminescence spectra.The triplet state and ~1O_2 lifetimes of Rose Bengal as a model photosensitizer in different solvents are determined,and the obtained results agr...