Asymmetric epoxidation of α, β-unsaturated ketones using α,α-diarylprolinols as catalysts

• 来源期刊: 科学通报(英文版)
• 学科: 化学
• 关键词: β-不饱和酮 不对称环氧化 催化剂 对映选择性 三氟甲基 脯氨酸 查尔酮 甲基酮
• 年，卷（期）: 2010,（17）
• 所属期刊栏目: REVlEW
• 页码范围: 1712-1722
• 页数: 11页
• 分类号: O623.12 TQ463.24
• 语种: 英文

摘要

Asymmetric epoxidation of α,β-unsaturated ketones has been extensively studied and several important procedures have been developed in the last decade. This review addresses the most significant advances in asymmetric epoxidation of α,β-unsaturated ketones using proline-derived α,α-diarylprolinols as catalysts. Special attention has been paid to the enantioselective epoxidation of chalcones, α,β-unsaturated trifluoromethyl, trichloromethyl ketones and β,γ-unsaturated α-keto esters based on the reseach of our group.