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摘要:
Blood pressure(BP)plays an important role in the development and progression of cardiovascular disease.Moreover,hypertensive patients often have additional cardiovascular risk factors.Despite the abundance of antihypertensive drug categories,satisfactory BP regulation is often difficult to achieve.A major cause of this difficulty to properly manage BP is the less than optimal adherence of subjects to treatment.This is often due to the various adverse effects of the antihypertensive drugs.Calcium channel blockers(CCB)have an established efficacy for reducing BP.However,their side effect of peripheral edema is often a cause for the discontinuation of treatment.Manidipine holds some unique properties differentiating it from the rest of the CCB class.It has a better safety profile with a lower incidence of peripheral edema.Moreover,there are indications that manidipine holds additional beneficial attributes,such as improvement of renal function and decrease of insulin resistance.
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篇名 Manidipine:A different dihydropyridine
来源期刊 世界高血压杂志 学科 医学
关键词 MANIDIPINE Hypertension Calcium channel BLOCKERS PERIPHERAL EDEMA RENAL function INSULIN resistance
年,卷(期) sjgxyzz_2011,(1) 所属期刊栏目
研究方向 页码范围 3-6
页数 4页 分类号 R
字数 语种
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研究主题发展历程
节点文献
MANIDIPINE
Hypertension
Calcium
channel
BLOCKERS
PERIPHERAL
EDEMA
RENAL
function
INSULIN
resistance
研究起点
研究来源
研究分支
研究去脉
引文网络交叉学科
相关学者/机构
期刊影响力
世界高血压杂志
不定期
2220-3168
北京市朝阳区东四环中路62号楼远洋国际中
出版文献量(篇)
53
总下载数(次)
0
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