胆汁管肿瘤的标记

• 作者: Giulia Malaguarnera Maria Giordano Isabella Paladina Alessandra Rando Mario Uccello Francesco Basile Antonio Biondi Santo Carnazzo Innocenza Alessandria Clorinda Mazzarino
• 来源期刊: 世界胃肠肿瘤学杂志：英文版（电子版）
• 学科: 医学
• 关键词: BILE duct TUMORS CHOLANGIOCARCINOMA Tumor markers CARBOHYDRATE ANTIGEN 19-9 CHROMOGRANIN A
• 年，卷（期）: 2011,（4）
• 页码范围: 49-59
• 页数: 11页
• 分类号: R735.8

摘要

Biliary tract carcinomas are relatively rare,representing less than 1%of cancers.However,their incidence has increased in Japan and in industrialized countries like the USA.Biliary tract tumors have a poor prognosis and a high mortality rate because they are usually detected late in the course of the disease;therapeutic treatment options are often limited and of minimal utility.Recent studies have shown the importance of serum and molecularmarkers in the diagnosis and follow up of biliary tract tumors.This review aims to introduce the main features of the most important serum and molecular markers of biliary tree tumors.Some considerable tumor markers are cancer antigen 125,carbohydrate antigen 19-9,carcinoembryonic antigen,chromogranin A,mucin 1,mucin 5,alpha-fetoprotein,claudins and cytokeratins.