MicroRNA links obesity and impaired glucose metabolism

• 来源期刊: 细胞研究（英文版）
• 年，卷（期）: 2011,（6）
• 页码范围: 864-866
• 页数: 3页
• 语种: 英文
• DOI: 10.1038/cr.2011.78

摘要

The current obesity pandemic, which is in part a consequence of social trends toward higher energy intake and reduced energy expenditure, is expected to result in type 2 diabetes (T2DM)and considerable downstream morbidity, mortality and incremental costs to healthcare systems around the world [ 1 ].The number of T2DM cases is increasing at a worrisome rate and is expected to double within the next 20 years.However, the molecular mechanisms that underlie individual changes in the predisposition to obesity and T2DM remain obscure.